Snoring & Obstructive Sleep Apnea Risks in Patients with Pulmonary Embolism
Obstructive sleep apnea (OSA) is associated with prothrombotic effects that could lead to venous thromboembolic disease.
The researchers performed a prospective cross-sectional study to determine the prevalence of snoring and risk of OSA in patients with acute pulmonary embolism (PE).
Research evaluated 270 consecutive patients who underwent a computed tomographic angiogram for suspected PE. Patients without PE served as a control group.
Demographic and clinical characteristics were analyzed.
The Berlin Questionnaire was used to determine the presence of snoring and the risk of OSA. A subset of patients also underwent formal nocturnal polysomnography.
PE was present in 71 (26%) of the 270 patients who underwent a computed tomographic angiogram.
When compared with patients without PE, patients with PE had a significantly higher prevalence of snoring (75% vs 50%, odds ratio = 2.91, 95% confidence interval: 1.60, 5.33, P = 0.001) and an increased risk of having OSA, as defined by the Berlin Questionnaire (65% vs 36%, odds ratio = 3.25, confidence interval: 1.84, 5.72, P < 0.001).
Results from the multivariate analysis showed that PE was independently associated with risk of OSA (OR = 2.78, P = 0.001).
Researchers found a higher prevalence of snoring and high risk of OSA in patients diagnosed with acute PE, in comparison with patients in whom PE was suspected but ruled out.
This association might be independent of other risks factors common to both OSA and PE. Therefore, OSA may represent a risk factor for the development of PE.
Detailed findings of this research study are published in the August issue of the Journal “SLEEP”.
Citation: Epstein MD; Segal LN; Ibrahim SM; Friedman N; Bustami R. Snoring and the risk of obstructive sleep apnea in patients with pulmonary embolism. SLEEP 2010;33(8):1069-1074.
Tagged with: Berlin Questionnaire • Obstructive Sleep Apnea • OSA • Polysomnography • prothrombotic effects • PULMONARY EMBOLISM • Sleep Apnea • Snoring
Filed under: Obstructive Sleep Apnea • Polysomnography • Sleep Apnea • Sleep Apnea Effects • Sleep Apnea Research • Sleep Apnea Study • Snoring
Like this post? Subscribe to my RSS feed and get loads more!
great post, thanks. theres great stuff in this blog
I just thinking i’d post and let you know your information sites is useful for disclosed the practical solution.I genuinely love your blog.Most effectively and efficiently, the content is in experience the right on this worth although subject. I concur along with your results and will excitedly seem forward to your forthcoming revisions. Really saying thanks will not just be enough, for your amazing lucidity inside your advice. I will quickly take your rss feed to remain informed of any updates.Honest work and significantly accomplishment in the show results and online business efforts.Regardless maintain up the superior function.Many thanks.