In a recently concluded research study the researchers aimed to evaluate the efficacy of oral appliance (OA) treatment for subjects with severe obstructive sleep apnea (OSA) and to determine the dental parameters associated with treatment outcomes.
This study uses a prospective longitudinal design. Consecutive Chinese subjects with severe obstructive sleep apnea (OSA ) who refused continuous positive airway pressure treatment were recruited. Their dental measurements were taken from lateral cephalometric radiographs. Polysomnograms with OA were repeated at 3 months and 1 year. Blood pressure was taken in the morning after sleep studies. 
Thirty-four subjects were evaluated at 3 months and 1 year according to the principle of intention-to-treat analysis. OA reduced AHI significantly in subjects with favorable responses, from 49.3 (37.4–67) to 12.5 (6.1–15.7), p?<?0.001 at 3 months and from 47.5 (41.1–72.9) to 13.1 (6.0–14.0), p?<?0.001 at 1 year. These OSA subjects had an increased overjet at baseline compared to those with unfavorable responses (p???0.05). Systolic blood pressure was significantly reduced in those hypertensive OSA subjects after 3 months and 1 year of treatment.  
Oral Appliances(OA) reduce the severity of sleep apnea, and the effect is maintained at 1 year in subjects with retrognathism. OA appears to reduce systolic blood pressure in hypertensive OSA subjects at 3 months and 1 year.
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Filed under: Clinical Research • Clinical Trials • CPAP • CPAP Device • CPAP Therapy • Dental Appliances • High Blood Pressure • Obstructive Sleep Apnea • Oral Appliances • Sleep • Sleep Apnea • Sleep Apnea Devices • Sleep Apnea Effects • Sleep Apnea News • Sleep Apnea Research • Sleep Apnea Study • Sleep Apnea Treatment

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