Treatment with pregabalin significantly improved sleep and pain in patients with fibromyalgia, according to research presented at the 63rd annual meeting of the American Academy of Neurology, in Honolulu (S27.003).
According to the researchers the improvement in total sleep time was comparable to that seen with standard, FDA-approved sleep-promoting agents such as zolpidem [Ambien, Sanofi-aventis] or eszopiclone [Lunesta, Sunovion Pharmaceuticals],
The researchers enrolled 119 patients, 103 of who were women, to treatment with pregabalin (300-450 mg per day) or placebo in a randomized double-blind fashion. Patients had a mean age of 48.4 years. Dose adjustment took place in the first 14 days, followed by maintenance dosing until day 29. After a two-week taper and washout period, patients repeated the protocol in the other study arm. Read the rest of this entry
The new neural network-based screening tool diagnoses sleep apnea based on a patient’s answers to questions about body mass index, neck size, the presence of hypertension and other clinical characteristics.
Between 30 and 50 percent of cardiovascular patients are believed to suffer from this potentially life-threatening condition, which prevents sufficient air from getting into the lungs. Many of them are undiagnosed.
In heart patients, obstructive sleep apnea can trigger, heart attacks , atrial fibrillation and stroke. Read the rest of this entry
It could be a serious issue that needs your attention, according to a sleep expert at Baylor College of Medicine.
“Loud snoring, daytime sleepiness and waking up with a sore throat in the morning are all symptoms of sleep apnea,” said Dr. Mary Rose, assistant professor of pulmonary, critical care and sleep medicine at BCM.
Categories of Sleep Disorders
Sleep apnea is a respiratory sleep disorder characterized by pauses in breathing during sleep, said Rose.
Generally, these pauses are defined as apneas, complete cessation of breathing; hypopneas, a 30 percent reduction of breathing; or respiratory effort related arousals, awakenings due to disrupted breathing. When people have more than five of these events per hour of sleep, they are classified as having sleep apnea, said Rose. Read the rest of this entry
People with fibromyalgia who are also obese have greater sensitivity to pain, more impaired sleep,sleep disorders like obstructive sleep apnea, and less physical strength than their non-obese counterparts, according to new findings from a prospective study.
“Obesity seems to be a big barrier to fibromyalgia patients getting better,” said lead author Akiko Okifuji, PhD, professor in the Department of Anesthesiology’s Pain Research and Management Center at the University of Utah, Salt Lake City (J Pain 2010;11:1329-1337).
Previous research demonstrated that in the United States, obese individuals generally have a heightened sensitivity to nociceptive pain and a higher frequency of painful conditions, such as headache and back pain (e.g., Psychiatry Res 1983;8:119-125), and as many as 75% of patients with fibromyalgia are overweight or obese. Although the current study did not address why the correlation between weight and pain exists, the investigators concluded that weight reduction interventions may be pivotal to treating fibromyalgia. Read the rest of this entry