Cysteine is a Biomarker For Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is a risk factor for a number of cardiovascular conditions. Although homocysteine (Hcy) and cysteine (Cys) are regarded as cardiovascular risk factors, few studies have analyzed Hcy and Cys plasma concentrations in patients with Obstructive sleep apnea (OSA). The aim of this study was to evaluate the role of Hcy and Cys in Obstructive sleep apnea (OSA) in comparison with subjects without Obstructive sleep apnea (OSA)and to determine the possible influence of obesity on these variables.

Patients who submitted to polysomnography studies were recruited to engage in an 8-h fasting period for blood sample withdrawal, physical examination, ECG, and echocardiogram. A subgroup of lean patients with Obstructive sleep apnea (OSA)(BMI < 25 kg/m2) were analyzed to rule out the influence of obesity. Fifteen patients were randomly assigned to participate in a continuous positive airway pressure (CPAP) protocol to assess the influence of Obstructive sleep apnea (OSA)treatment on the obtained measurements.

A total of 75 patients and 75 control subjects matched for age and sex were analyzed. The Cys plasma levels were higher in patients with Obstructive sleep apnea (OSA) compared with control subjects (490.16 ± 67.00 ?mol/L vs 439.81 ± 76.12 ?mol/L, respectively, P < .01); however, the Hcy plasma levels did not differ between groups. Cys plasma levels were also higher in theObstructive sleep apnea (OSA) lean subgroup when compared with lean control subjects (484.21 ± 71.99 ?mol/L vs 412.01 ± 70.73 ?mol/L, respectively, P = .009). There was a significant decrease of Cys plasma levels after 6 months of CPAP effective therapy.

Cys is a potential biomarker of Obstructive sleep apnea (OSA) in obese and nonobese patients and is reduced after effective Obstructive sleep apnea (OSA) treatment.

Instant Diagnostic Systems Awarded Accreditation

Instant Diagnostic Systems (IDS), an Independent Diagnostic Testing Facility (IDTF) that specializes in home-based diagnostic testing, has earned The Joint Commission’s Gold Seal of Approval for accreditation. The accreditation award recognizes IDS’s dedication to continuous compliance with The Joint Commission’s standards in ambulatory health, telehealth, and sleep studies.

Mark Sorrells, president and CEO of IDS, said, ”Although accreditation is not a requirement for our type of health care facility in most jurisdictions, IDS felt it was important to pursue accreditation through The Joint Commission to demonstrate our commitment to providing high-quality health care to patients nationwide.”

Since 1975, The Joint Commission has developed standards for outpatient ambulatory care organizations. These standards address important functions relating to the care of patients and the management of an ambulatory care organization; and are developed in consultation with health care experts, providers, measurement experts, and patients.

“As the largest provider of overnight oximetry and home sleep testing in the United States, we hold ourselves accountable to a higher standard to provide high-quality, cost-effective diagnostic tests that patients can self-administer in their own homes,” Sorrells said. “With as many as 20 million Americans currently undiagnosed with sleep apnea, the number of home sleep tests performed by IDS is growing rapidly. Primary care physicians realize they can order a home sleep test and provide treatment to many of their patients without the patient going to an in-lab facility for the test at a significantly greater cost.“

Sleep Apnea Disorder/ [ Press Relese ] / The Healthy Trucking Association of America (HTAA) Summit will be the first venue to exhibit the new Transcend Sleep Apnea Therapy System. To be held at the Omni Hotel at CNN Center in Atlanta on March 1-3 this year, the HTAA Summit is the trucking industry’s premiere health and wellness event focused on improving the health of the nation’s professional driver population. Attracting trucking fleet safety directors, HR directors, recruitment and retention managers, and other fleet executives and industry leaders, this year’s Summit will feature sessions on sleep disorders, obesity and weight loss, hypertension and heart health, respiratory health, diabetes, and more.

Transcend is a new wearable obstructive sleep apnea ( OSA) therapy device designed to overcome hurdles associated with using a bulky, hassle-ridden traditional CPAP. Weighing about 1 lb, the FDA-approved Transcend is the smallest CPAP on the market. It is easy to operate, uses low power, replaces the messy humidification chamber with heat moisture exchange technology, and has optional battery back-up. Transcend will be on display at the Summit on March 2 and 3. Read the rest of this entry

A New Dental Device Helps Sleep Apnea Patients

A good night’s sleep has a direct connection to a healthy lifestyle. If you’re tossing and turning, or if you’re like the 37 million American’s who reportedly suffer from obstructive sleep apnea, you could be putting yourself at risk.

“It is a serious problem, because when you stop breathing obviously, your oxygen level in your blood goes down, and it affects basically all the organs in your body,” said Dr. Stephen Seidler with Orange City Dental Care.

If left untreated, sleep apnea can lead to obesity, heart disease and even stroke and that’s why coming to the dentist’s office could be the key to solving your issues.

Dr. Seidler explains how a small device, similar to a retainer, has helped some of his patients. “It snaps in on the bottom and the front (of your teeth),” he says. “It’s keeping the lower jaw forward so it doesn’t allow it to fall back.” FOX 35’s Talitha Vickers spoke with Dr. Stephen who demonstrates the device in the accompanying video. 

Dental device helps with sleep apnea: MyFoxORLANDO.com

Research and Markets  has announced the addition of the “Japan Patient Monitoring and Diagnostic Systems Market Opportunity and Growth Trend Forecast till 2016” report to their offering.

The Market Intelligence report provides critical market data for Japan patient monitoring and diagnostics market and its product categories. The data includes market size in terms of value and volume; average selling price for each product type, growth trends and market shares of companies at sector and category level.

Its vital cross category comparison and cross sub-category comparison section makes analysis very handy for company professionals. The report helps professionals in mapping market size, competition, understanding historic and future growth trends.

It covers important categories such as blood pressure monitors, cardiovascular monitoring systems, blood glucose monitoring devices, hearing diagnostics, micro-electromechanical systems multiparameter patient monitors, remote monitoring systems, sleep apnea diagnostic systems and wireless hospital ambulatory monitors.

Less sleep is associated with an increased risk for colon cancer, according to a recent report in the journal Cancer (Thompson CL et al. 2011;117:841-847). The investigators found that individuals who averaged less than six hours of sleep each night had a nearly 50% higher risk for developing colorectal adenomas than individuals who slept at least seven hours a night.

“To our knowledge, this is the first study to report a significant association between sleep duration and colorectal adenomas, supporting short duration of sleep as a novel risk factor for the development of early colorectal neoplasia,” the study authors wrote.

The increased risk for colorectal adenoma associated with less sleep was comparable to the risk associated with well-known risk factors for colon cancer: having a first-degree relative with colorectal cancer or ingesting high quantities of red meat. Read the rest of this entry

Sleep is a precious gift to human nature. But for over 87 million Americans, snoring and sleeping go hand-in-hand. Since snoring is often passed off as a simple annoyance, many people don’t understand the potential health problems snoring can cause. Snoring may be a warning sign of Obstructive Sleep Apnea (OSA) in which a person stops breathing at times during the night and up to 7 minutes over the course of one night.

In fact, sleep apnea and snoring have been linked to very serious health issues such as heart attack and stroke. It’s also estimated that there are over 40 million Americans with sleep disorders and over 90% of them are left undiagnosed and untreated. In such milieus, it is imperative for folks to look into the World Wide Web for Snoring Treatments and Snoring Remedies. One name which stands out in the crowd due to its sheer resourcefulness and professionalism is Stop Snoring Austin. Read the rest of this entry

Research and Markets has announced the addition of the “Germany Patient Monitoring and Diagnostic Systems Market Opportunity and Growth Trend Forecast till 2016″ report to their offering.

The Market Intelligence report provides critical market data for Germany patient monitoring and diagnostics market and its product categories. The data includes market size in terms of value and volume; average selling price for each product type, growth trends and market shares of companies at sector and category level.

Its vital cross category comparison and cross sub-category comparison section makes analysis very handy for company professionals. The report helps professionals in mapping market size, competition, understanding historic and future growth trends.

It covers important categories such as blood pressure monitors, cardiovascular monitoring systems, blood glucose monitoring devices, hearing diagnostics, micro-electromechanical systems multiparameter patient monitors, remote monitoring systems, sleep apnea diagnostic systems and wireless hospital ambulatory monitors.

Factors Influencing CPAP Adherence

Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea syndrome (OSAS). Consistent adherence to CPAP improves the patient’s longevity and quality of life as well as public safety.

However, nonadherence is a significant contributor to the growing burden of untreated obstructive sleep apnea syndrome (OSAS), and is associated with negative consequences for the patient, public safety, and the healthcare system.

The use of CPAP is a classic example of an effective treatment for which adherence is extremely variable. This paper examines a multiplicity of factors that influence CPAP adherence.

These factors are traditionally thought of in terms of patient and equipment variables, but in addition physician, family, healthcare facility, and governmental issues all contribute to CPAP adherence. These factors are reviewed and pragmatic recommendations are made for improving clinica practice.

A recently concluded research study investigated to determine if clinical data and Nasal Obstruction Symptom Evaluation (NOSE) scores can be used to identify patients at risk for obstructive sleep apnea (OSA).

Intake surveys using the NOSE, Epworth Sleepiness Scale (ESS), and Snore Outcomes Scale (SOS) were administered to new patients visiting a facial plastic surgery practice and a rhinology practice. 

The odds ratio (OR) for an ESS score higher than 10 was 2.98 (95% confidence interval [CI], 1.17-7.57) when snoring was present; 5.5 (95% CI, 1.35-22.58) when the NOSE score was 10 or higher; and 3.3 (95% CI, 0.98-11.0) when a deviated septum was found on clinical examination. The probability of an elevated ESS score was 88% when all 3 factors were present and 56% when the NOSE score was not elevated. Receiver operating characteristic analysis with predictors “snore” and NOSE score of 10 or higher had an area under the curve of 0.72. With a probability cutoff of 0.5, the sensitivity was 30%, and the specificity 90%.

Sinonasal surgery is among the most common outpatient procedures performed in the United States each year. Many patients undergoing sinonasal surgery have undiagnosed obstructive sleep apnea(OSA)  or nasal obstruction, a known risk factor for obstructive sleep apnea(OSA). Patients with obstructive sleep apnea(OSA) have unique perioperative needs. In patients with nasal obstruction, a deviated septum, and/or snoring, there is an association between the NOSE score and the ESS score. The NOSE survey may serve as a simple screening instrument instead of the ESS for patients at risk for undiagnosed obstructive sleep apnea(OSA) and special perioperative needs.

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