SleepApneaDisorder/[Press Release ] / Cephalon, Inc. today announced that Risk Evaluation and Mitigation Strategies (REMS) for its medications NUVIGIL® (armodafinil) Tablets [C-IV] and PROVIGIL® (modafinil) Tablets [C-IV] have been approved by the U.S. Food and Drug Administration (FDA).  Both the NUVIGIL and PROVIGIL REMS consist of a Medication Guide to inform patients about the potential risks associated with the use of these medications, a communication plan and a timetable for submission of assessments of the REMS.  The communication plan includes a Dear Healthcare Professional Letter, a Prescriber Brochure, a Pharmacist Action Letter and a dedicated REMS Internet Site. The introduction of the NUVIGIL and PROVIGIL REMS programs is consistent with the company’s commitment to safe and appropriate use of its medications.   Read the rest of this entry

Pediatric obstructive sleep apnea syndrome (OSAS) is associated with neurocognitive and endothelial dysfunction.

However, it is unclear whether these two frequent morbidities of OSAS in children represent similar or different underlying pathophysiological processes, because they have never been concurrently assessed in children.

Consecutive children (ages 5–8 years) with polysomnographically based OSAS underwent cognitive battery evaluation (Differential Ability Scales and the NeuroPsychological Assessment Battery) and cuff-occlusion hyperemic tests for assessment of endothelial function. Read the rest of this entry

Sleep Apnea Awareness is Increasing

According to the American Academy of Dental Sleep Medicine, about 18 million Americans suffer from obstructive sleep apnea, and roughly 80 to 90 percent of these people remain undiagnosed and untreated. Dr. William Kohler, a spokesman for the American Academy of Sleep Medicine, said awareness of sleep disorders, including obstructive sleep apnea, has gone up in recent years. Though Kohler, also medical director of the Florida Sleep Institute in Spring Hill, Fla., said he doesn’t know if the disorders themselves are on the rise, it’s a distinct possibility.

Though people often kid about snoring and the like, obstructive sleep apnea is a serious problem. People with the illness can stop breathing hundreds of times a night. The disorder also can contribute to an increased risk for high blood pressure, heart attack, stroke and other problems. “Sleep apnea is nothing to joke about,” Kohler said.

According to a new report by iData Research , the leading global authority in medical device and pharmaceutical market research, the U.S. patient monitoring market is expected to reach almost $4 billion by 2017. Multi-parameter vital-sign devices represented the majority of the patient monitoring market in 2010, with the home telehealth segment growing over 17% in 2010 and the hospital wireless telemetry monitoring segment growing at high double-digit rates. The second largest segment of this market was pulse oximetry, which is expected to exceed $934 million by 2017. Read the rest of this entry

 

A research was conducted with an Objective to describe experience treating retroglossal and base-of-tongue collapse in children and young adults with obstructive sleep apnea using combined genioglossus advancement (Repose THS; MedtronicENT, Jacksonville, Florida) and radiofrequency ablation of the tongue base.

The team of researchers included experts from Pediatric Otolaryngology–Head and Neck Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio. Dr Wootten is now with the Department of Otolaryngology–Head and Neck Surgery, Vanderbilt University, Nashville, Tennessee.

Retrospective institutional review board–approved analysis of 31 operations was conducted at the tertiary pediatric medical center. In all thirty-one patients with a mean age of 11.5 years (age range, 3.1-23.0 years).  Read the rest of this entry

As Americans get heavier and heavier, the incidence of obstructive sleep apnea increases, and results from two clinical studies presented at ANESTHESIOLOGY 2010 reinforce the need for physicians to screen for the disorder prior to surgery in order to appropriately manage the patient in the operating room.

“If patients with unidentified obstructive sleep apnea undergo surgery, they may have an increased chance of experiencing complications during and after surgery,” said Frances Chung, F.R.C.P.C., investigator on both studies and Professor, Department of Anesthesia, University Health Network, University of Toronto. “A growing amount of evidence suggests that obstructive sleep apnea is associated with heart and lung disease, diabetes mellitus and a higher rate of early death.” Read the rest of this entry

School Children Are Sleep Deprived

SleepApneaDisorder/[Press Release ]/ Newport Beach, CA /October 15, 2010/Glidewell Laboratories, industry-leading provider of dental lab products and services, announced today that the company, in partnership with 1-800-Snoring, will offer a free webinar titled “How to Recognize Patients with Snoring and Sleep Apnea in Your Practice.”

The one-hour online course will take place Oct. 27, 2010, at 10 a.m. (EDT) (https://www1.gotomeeting.com/register/254800961) and 1 p.m. (PDT) (https://www1.gotomeeting.com/register/897247560), and will show dentists how to recognize the signs and symptoms of snoring and OSA. Nearly 30 percent of the U.S. population is afflicted with a Sleep Disordered Breathing condition. This webinar will discuss the benefits of adding snoring and OSA treatment to your dental practice. It will also address how to identify and speak with these patients. Read the rest of this entry

Sleep Disorders and Autism in Children

Sleep disorders affect up to two-thirds of children with the Autism (or autistic) Spectrum Disorder (ASD) . Insomnias are predominant; however, parasomnias, breathing disorders, and movement disorders have also been reported. Recent work in ASD genetics suggests a relationship between polymorphisms in the biological clock genes, and autism.

Although the effects of sleep disorders are difficult to separate from the effects of neurodevelopmental disability in general, insomnia is important to treat because it may exacerbate challenging behaviors, hyperactivity, cognitive deficits, headaches, and seizure frequency.

For sleep difficulties related to disrupted circadian cycles, it may be helpful to limit daytime sleeping and caffeine intake and to ensure regular exercise. Exogenous treatment with melatonin may decrease time to sleep onset.

Psychiatric comorbidities, such as anxiety and attention-deficit/hyperactivity disorder, and medical comorbidities, such as epilepsy, sleep disorders, and Tourette syndrome, are frequent in ASD.

What To Do When One Stops Breathing?

Sleep Apnea elevates the overall risk of heart attack, diabetes and stroke and several researches have established such links with clinical studies. Here are few extremely helpful tips as what you should do when a loved one stops breathing;

  • Check the pulse for a heartbeat.
  • Try artificial ventilation (mouth to mouth restoration of air).
  • If you are overweight, weight reduction may improve your snoring or sleep apnea and enlarge the airway size.
  • Elevating the head of your bed and avoiding sleeping on your back may be helpful. A common way to train you to not sleep on the back is to place a tennis ball in a sock pinned to the back of a sleep shirt or placed in a pocket sewn into the shirt.
  • Improve the amount and regularity of sleep. One should go to sleep and wake up at approximately the same time every day. Try to get at least seven to eight hours of sleep a night. Snoring and sleep apnea is often worse if you are overtired. Read the rest of this entry
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